Specific IgG antibodies in sera in patients with penicillin allergy. It was not possible to register seasonal variations of the same magnitude of timothy- specific IgA antibodies. Both IgG1 and IgG4 antibodies specific for timothy showed seasonal variations of a similar degree. It was possible to register clearcut seasonal variations with postseasonally boosted antibody levels not only of timothy- specific IgE but also of IgG antibody. IgG antibodies were also assayed by a Sepharose-protein-A technique with radiolabelled timothy allergens as the antigen. Timothy- specific IgG and IgA antibodies were quantified by a refined ELISA in which covalent binding of the antigen to the polystyrene solid phase had been performed.
The sera were assayed for contents of timothy- specific IgE antibodies by RAST. Serum samples were collected from eight grass pollen hypersensitive children during a 4-year period.
Nordvall, S L Larsson, P H Johansson, S G Timothy- specific IgG antibody levels vary with the pollen seasons.
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